| Speer, Henry | Surry (139), Stokes (2), Rowan (1), plus 2 grants in 2 other counties; total 144 grants and 30915 acres, 1779-1813 |
| Speer, Jacob | Surry (2); 420 acres, 1779-1802 |
| Speer, Jacob, Jr. | Surry (2); 300 acres, 1780-1802 |
| Speer, James J. | Surry (1); 17 acres, 1829 |
| Speer, John | Surry (5), Buncombe (2), Pitt (1); total 8 grants and 1989 acres, 1783-1813 |
| Speer, Joshua Kennerly | Surry (1); 150 acres, 1787 |
| Speer, Levi | Surry (2); 337 acres, 1780-1806 |
| Speer, Phillip | McDowell (1); 66 acres, 1871 |
| Speer, Richard | Surry (3); 810 acres, 1789-1797 |
| Speer, Robert | Surry (2); 300 acres, 1782-1787 |
| Speer, Samuel | Surry (9); 314 acres, 1799-1835 |
| Speer, William | Pitt (2), Surry (1); total 3 grants and 431 acres, 1782-1905 |
| Speerpoint, Joseph | Davidson TN (1); 640 acres, 1787 |
| Speers, Henry | Surry (1), Rowan (1); total 2 grants and 440 acres, 1783 |
| Speght, Frances | Craven (1); 573 acres |
| Spegle, Martain | Lincoln (1); 100 acres, 1787 |
| Speigel, Moses | Lincoln (1); 25 acres |
| Speigel, Samuel | Lincoln (1); 67 acres |
| Speight, Dempsey | Dobbs (1); 640 acres, 1779 |
| Speight, Francis | Chowan (4), Glasgow (2), Dobbs (2), plus 3 grants in 2 other counties; total 11 grants and 4160 acres, 1743-1797 |
| Speight, James | Sumner TN (1); 365 acres, 1793 |
| Speight, Jeremiah | Gates (1); 252 acres, 1783 |
| Speight, John | Dobbs (1), Craven (1); total 2 grants and 940 acres, 1780-1799 |
| Speight, John W. | Craven (1); 39 acres, 1857 |
| Speight, Joseph | Gates (1), Sumner TN (1); total 2 grants and 811 acres, 1783-1793 |
| Speight, L. C. | Brunswick (1); 25 acres, 1849 |
| Speight, Mary | Craven (1); 185 acres |
| Speight, Moses | Dobbs (1), Sumner TN (1); total 2 grants and 715 acres, 1793 |
| Speight, Richard Dobbs | Eastern District TN (1); 200 acres, 1794 |
| Speight, Samuel | Dobbs (4), Glasgow (2), Greene (1); total 7 grants and 1877 acres, 1779-1803 |
| Speight, Seth | Glasgow (5), Dobbs (4), Greene TN (1); total 10 grants and 1796 acres, 1780-1798 |
| Speight, Simon | Jones (3), Craven (2); total 5 grants and 580 acres, 1764-1784 |
| Speight, Thomas | Craven (4), Perquimans (3), Chowan (1); total 8 grants and 2296 acres, 1696-1787 |
| Speight, William | Craven (12), Dobbs (11), Glasgow (6), plus 6 grants in 5 other counties; total 35 grants and 8505 acres, 1696-1846 |
| Speight, William, Jr. | Craven (2); 525 acres, 1786-1799 |
| Speights Branch | Wake (1); 640 acres, 1779 |
| Speights, Simon | Pitt (1); 0 acres |
| Speights, William | Wake (1); 398 acres, 1779 |
| Speigle, Davault | Lincoln (1); 5 acres, 1814 |
| Speigle, Devault | Lincoln (1); 4 acres, 1812 |
| Speigle, Martin | Lincoln (1); 154 acres, 1789 |
| Speigle, Samuel | Lincoln (2); 137 acres |
| Speir, James | Edgecombe (3); 660 acres, 1742-1758 |
| Speir, John | Edgecombe (2), Pitt (1); total 3 grants and 909 acres, 1739-1802 |
| Speir, William | Pitt (2), Edgecombe (2), Beaufort (1); total 5 grants and 1754 acres, 1740-1802 |
| Spell, H. L. | Sampson (1); 14 acres, 1886 |
| Spell, Hardy | Sampson (2); 30 acres, 1833-1857 |
| Spell, Harris | Johnston (1); 100 acres |
| Spell, J. H. | Sampson (1); 1 acres, 1884 |
| Spell, J. J. | Sampson (3); 44 acres, 1874-1877 |
| Spell, James | Sampson (1); 16 acres, 1845 |
| Spell, James M. | Sampson (1); 495 acres, 1843 |
| Spell, John | Edgecombe (2); 1478 acres, 1754-1782 |
| Spell, Jones | Edgecombe (1); 513 acres, 1761 |
| Spell, L. H. | Sampson (1); 15 acres, 1858 |
| Spell, R. L. | Sampson (2); 152 acres, 1879-1882 |
| Spellar, James | Duplin (1); 30 acres, 1784 |
| Spellars Creek | Martin (1); 400 acres, 1784 |
| Spellars, Thomas | Martin (1); 72 acres |
| Speller, Henry | Bertie (3), Chowan (1); total 4 grants and 1528 acres, 1719-1726 |
| Speller, Thomas | Tyrrell (1), Bertie (1); total 2 grants and 305 acres, 1745-1811 |
| Spelling, Timothy | Bertie (1); 300 acres, 1725 |
| Spellmam, N. J. | Cherokee (1); 100 acres, 1855 |
| Spelman, Harman | Rowan (1); 640 acres, 1784 |
| Spelman, John | Perquimans (1); 350 acres, 1694 |
| Spelman, Simon | Sumner TN (1); 640 acres, 1797 |
| Spence, Alexander | Pasquotank (1); 100 acres, 1715 |
| Spence, Arthur | Currituck (1); 59 acres, 1806 |
| Spence, David | Surry (1), Middle District TN (1), Davidson TN (1); total 3 grants and 3340 acres, 1789-1794 |
| Spence, E. T. | Cumberland (1); 1 acres, 1907 |
| Spence, Elisha | Cumberland (1); 20 acres, 1820 |
| Spence, Graves | Pasquotank (1); 185 acres, 1751 |
| Spence, Hardy | Tyrrell (2); 350 acres, 1832-1847 |
| Spence, Hiziah | Wilkes (1); 50 acres, 1812 |
| Spence, Isaac | Duplin (1); 50 acres, 1799 |
| Spence, James | Pasquotank (1), Davidson TN (1); total 2 grants and 868 acres, 1719-1787 |
| Spence, James H. | Macon (1); 100 acres, 1850 |
| Spence, Job | Sumner TN (1); 274 acres, 1793 |
| Spence, John | Cumberland (8), Wake (1), Surry (1), plus 1 grant in 1 other county; total 11 grants and 1238 acres, 1796-1832 |
| Spence, Joseph | Tyrrell (10); 1857 acres, 1779-1832 |
| Spence, Robert | Tyrrell (3), Randolph (1); total 4 grants and 450 acres, 1794-1821 |
| Spence, Thomas | Surry (3); 650 acres, 1782-1790 |
| Spence, William | Davidson TN (1); 640 acres, 1789 |
| Spencer Creek | Montgomery (4); 550 acres, 1803-1882 |
| Spencer Mountain | Lincoln (1), Gaston (1); total 2 grants and 56 acres, 1902 |
| Spencer's Creek | Montgomery (2); 81 acres, 1851-1908 |
| Spencer, Abraham | Guilford (1); 300 acres, 1784 |
| Spencer, Absolom | Burke (1); 100 acres |
| Spencer, Alexander | Randolph (5), Montgomery (1); total 6 grants and 941 acres, 1840-1852 |
| Spencer, Ama | Montgomery (1); 100 acres, 1844 |
| Spencer, Ambrose | Ashe (2); 45 acres, 1886-1895 |
| Spencer, Ball | Surry (1); 100 acres, 1778 |
| Spencer, Benjamin | Caswell (1); 200 acres, 1783 |
| Spencer, Burrel | Ashe (1); 40 acres, 1805 |
| Spencer, Christopher C. | Hyde (2); 15 acres, 1889 |
| Spencer, Clark | Montgomery (1); 100 acres, 1844 |
| Spencer, Colon G. | Moore (1); 3 acres, 1924 |
| Spencer, Creek | Montgomery (1); 40 acres, 1816 |
| Spencer, David M. | Ashe (1); 50 acres, 1873 |
| Spencer, Edward | Hyde (21); 11600 acres, 1774-1775 |
| Spencer, Elias | Montgomery (2); 200 acres, 1795-1804 |
| Spencer, Elijah | Montgomery (5); 655 acres, 1795-1809 |
| Spencer, Elizabeth | Montgomery (1); 100 acres, 1844 |
| Spencer, Fenner S. | Hyde (1); 7 acres, 1889 |
| Spencer, George | Randolph (1), Montgomery (1); total 2 grants and 160 acres, 1840-1844 |
| Spencer, Greenville | Stokes (1); 50 acres, 1829 |
| Spencer, H. B. | Ashe (1), Hyde (1); total 2 grants and 12 acres, 1883-1891 |
| Spencer, Hardy | Tyrrell (2); 100 acres, 1852 |
| Spencer, Henry | Ashe (1); 45 acres, 1872 |
| Spencer, Isaac | Tyrrell (1), Randolph (1), Ashe (1); total 3 grants and 301 acres, 1803-1840 |
| Spencer, Isam | Ashe (1); 86 acres, 1852 |
| Spencer, J. P. | Brunswick (1); 11 acres, 1911 |
| Spencer, J. W. | Catawba (1); 0 acres, 1908 |
| Spencer, James | Hyde (1), Eastern District TN (1); total 2 grants and 647 acres, 1793-1850 |
| Spencer, Jeremiah | Orange (1); 624 acres, 1782 |
| Spencer, Jesse | Randolph (1), Johnston (1); total 2 grants and 107 acres, 1806-1845 |
| Spencer, Jesse S. | Montgomery (1); 40 acres, 1854 |
| Spencer, John | Burke (5), Anson (4), Surry (3), plus 7 grants in 6 other counties; total 19 grants and 2854 acres, 1755-1865 |
| Spencer, John E. | Anson (1); 18 acres, 1884 |
| Spencer, John G. | Wilkes (1); 100 acres, 1836 |
| Spencer, John, Jr. | Burke (1); 150 acres, 1794 |
| Spencer, Johnson | Montgomery (6), Randolph (2); total 8 grants and 486 acres, 1833-1849 |
| Spencer, Johnston | Randolph (4), Montgomery (1); total 5 grants and 435 acres, 1795-1806 |
| Spencer, Joseph | Burke (8), Tryon (2), Buncombe (2), plus 1 grant in 1 other county; total 13 grants and 2320 acres, 1768-1799 |
| Spencer, Mary | New Hanover (1); 0 acres, 1883 |
| Spencer, Nathan | Montgomery (4), Randolph (2), Hyde (2); total 8 grants and 974 acres, 1760-1854 |
| Spencer, Robert | Wilkes (1); 22 acres, 1891 |
| Spencer, S. H. | Hyde (1); 10 acres, 1888 |
| Spencer, Samuel | Tryon (12), Anson (11), Grainger TN (7), plus 10 grants in 3 other counties; total 40 grants and 13920 acres, 1767-1854 |
| Spencer, Sarah | Montgomery (1); 300 acres, 1795 |
| Spencer, Seymore | Montgomery (4); 330 acres, 1809 |
| Spencer, Solloman | Ashe (1); 76 acres, 1840 |
| Spencer, Solomon | Ashe (3); 219 acres, 1849 |
| Spencer, T. B. | Hyde (1); 4 acres, 1890 |
| Spencer, Thomas | Davidson TN (3), Surry (1), Caswell (1), plus 1 grant in 1 other county; total 6 grants and 3620 acres, 1783-1792 |
| Spencer, Thomas Sharp | Davidson TN (2); 640 acres, 1788 |
| Spencer, U. L. | Moore (1); 73 acres, 1907 |
| Spencer, W. F. | Brunswick (1); 21 acres, 1953 |
| Spencer, William | Montgomery (6), Randolph (5), Anson (5), plus 11 grants in 8 other counties; total 27 grants and 3069 acres, 1757-1872 |
| Spencer, William S. | Anson (5); 357 acres, 1811-1818 |
| Spencer, Winston | Montgomery (1); 95 acres, 1855 |
| Spencer, Zachariah | Lincoln (1); 50 acres |
| Spencers Branch | Montgomery (3); 210 acres, 1786-1800 |
| Spencers Creek | Montgomery (16), Tyrrell (2), Tryon (2); total 20 grants and 1860 acres, 1773-1883 |
| Spencers Creek (tenn.) | Sumner TN (19), Davidson TN (10); total 29 grants and 17759 acres, 1787-1797 |
| Spencers Fork | Burke (2), Rutherford (1); total 3 grants and 400 acres, 1783-1808 |
| Spences Branch | Bladen (1); 100 acres, 1779 |
| Spencewest, Nathaniel | Currituck (1); 677 acres, 1761 |
| Spenns, James | Hawkins TN (1); 200 acres, 1793 |
| Sperlin, William | Ashe (1); 100 acres, 1853 |
| Sperry, Jesse | Wilkes (1); 95 acres, 1798 |
| Spevey, Thomas | Chowan (1); 494 acres, 1715 |
| Spewmarrow Creek | Granville (10); 4484 acres, 1748-1780 |
| Spewmorrow Creek | Granville (1); 640 acres, 1760 |
| Spiars Family | Tyrrell (1); 239 acres, 1762 |
| Spice Bottom Creek | Ashe (1); 98 acres, 1800 |
| Spice, Amos | Lincoln (2); 200 acres, 1794 |
| Spicer, Eliza | Onslow (1); 250 acres |
| Spicer, Fanny | Alleghany (1); 9 acres, 1912 |
| Spicer, Gideon | Wilkes (1); 77 acres, 1856 |
| Spicer, Harden | Wilkes (1); 37 acres, 1838 |
| Spicer, Hardin | Wilkes (2); 87 acres, 1836-1855 |
| Spicer, Harva | Wilkes (1); 50 acres, 1853 |
| Spicer, Henry | Surry (1); 100 acres |
| Spicer, J. B. | Wilkes (3), Alleghany (1); total 4 grants and 97 acres, 1883-1922 |
| Spicer, J. W. | Wilkes (2); 35 acres, 1880-1890 |
| Spicer, James | Onslow (1), New Hanover (1); total 2 grants and 180 acres, 1788-1789 |
| Spicer, James, Sr. | Onslow (1); 300 acres, 1788 |
| Spicer, John | Onslow (8), New Hanover (1), Wilkes (1); total 10 grants and 2065 acres, 1767-1884 |
| Spicer, John E. | Onslow (2); 200 acres, 1813 |
| Spicer, John F. | Onslow (1); 100 acres, 1836 |
| Spicer, John, Sr. | Onslow (1); 640 acres, 1788 |
| Spicer, Joseph | Wilkes (3), Johnston (2); total 5 grants and 1496 acres, 1779-1899 |
| Spicer, Joshua | Wilkes (1); 54 acres, 1891 |
| Spicer, Larkin | Wilkes (2); 68 acres, 1852-1860 |
| Spicer, M. F. | Wilkes (1); 50 acres, 1880 |
| Spicer, Robert | Surry (1); 190 acres, 1787 |
| Spicer, Samuel F. | Ashe (1), Wilkes (1); total 2 grants and 200 acres, 1851-1854 |
| Spicer, Sarah | Wilkes (1); 32 acres, 1846 |
| Spicer, William | Wilkes (3); 292 acres, 1806-1848 |
| Spicer, William, Jr. | Wilkes (1); 30 acres, 1845 |
| Spicers Creek | Montgomery (1); 50 acres |
| Spiegel, Devault | Lincoln (1); 28 acres, 1806 |
| Spiegle, Martin | Lincoln (1); 30 acres, 1789 |
| Spier, Dempsey | Wake (2), Edgecombe (1); total 3 grants and 562 acres, 1761-1790 |
| Spier, Henry | Surry (1); 200 acres, 1787 |
| Spier, James | Craven (3), Edgecombe (2); total 5 grants and 1540 acres, 1737 |
| Spier, John | Edgecombe (20), Beaufort (2), Tyrrell (1), plus 2 grants in 2 other counties; total 25 grants and 7692 acres, 1735-1799 |
| Spier, John Stuart | Pitt (1); 70 acres, 1784 |
| Spier, John, Jr. | Pitt (1); 200 acres, 1762 |
| Spier, Richard | Craven (2); 200 acres, 1738 |
| Spier, William | Edgecombe (8), Beaufort (4); total 12 grants and 3761 acres, 1736-1782 |
| Spier, Wright | Edgecombe (1); 66 acres, 1779 |
| Spiere, James | Edgecombe (1); 400 acres, 1742 |
| Spiere, John | Edgecombe (1); 160 acres, 1738 |
| Spiers, Absalom | Davidson TN (1); 360 acres, 1786 |
| Spiers, Dempsey | Wake (2); 347 acres, 1779-1785 |
| Spiers, Robert | Chatham (1); 50 acres, 1790 |
| Spiers, Spencer | Sumner TN (1); 640 acres, 1791 |
| Spiers, William | Johnston (1), Sumner TN (1); total 2 grants and 810 acres, 1791 |
| Spiggle, Martin | Lincoln (1); 200 acres, 1797 |
| Spight, Francis | Craven (1); 573 acres, 1740 |
| Spight, John | Jones (2), Edgecombe (1), Craven (1); total 4 grants and 792 acres, 1753-1799 |
| Spight, Miles W. | Onslow (1); 5 acres, 1832 |
| Spight, Sharp | Jones (1); 48 acres, 1799 |
| Spight, Simon | Jones (4), Craven (3); total 7 grants and 834 acres, 1766-1798 |
| Spight, Thomas | Jones (2), Craven (2), Perquimans (1); total 5 grants and 494 acres, 1718-1819 |
| Spight, William | Craven (3), Wake (1); total 4 grants and 1250 acres, 1751-1836 |
| Spight, William, Sr. | Craven (1); 400 acres, 1791 |
| Spights, Simon | Jones (1); 105 acres, 1790 |
| Spikebuck | Haywood (1); 640 acres |
| Spikes, Burrell | Johnston (1); 100 acres, 1782 |
| Spikes, Jones | Wilkes (1); 100 acres, 1846 |
| Spikes, Joseph | Bladen (1); 172 acres, 1796 |
| Spikes, Simon | Craven (1); 100 acres, 1767 |
| Spikes, Thomas | Johnston (4), Craven (1); total 5 grants and 650 acres, 1746-1779 |
| Spillar, James | New Hanover (1); 110 acres, 1789 |
| Spiller, Henry | Bertie (1); 516 acres, 1789 |
| Spiller, James | Sampson (9), Duplin (3), Onslow (2), plus 1 grant in 1 other county; total 15 grants and 4608 acres, 1785-1795 |
| Spiller, William | Onslow (1); 100 acres, 1799 |
| Spillers Creek | Martin (1); 300 acres, 1782 |
| Spillman, N. J. | Cherokee (3); 1480 acres, 1854 |
| Spine, John | Tyrrell (1), Jones (1); total 2 grants and 308 acres, 1742-1791 |
| Spinks, _______ | Randolph (1); 100 acres, 1787 |
| Spinks, Enoch | Randolph (3), Orange (2), Cumberland (2); total 7 grants and 1907 acres, 1761-1796 |
| Spinks, Garret | Randolph (2); 624 acres, 1854 |
| Spinks, John | Randolph (2); 160 acres, 1800-1851 |
| Spinks, Lewis | Randolph (5), Moore (1); total 6 grants and 750 acres, 1797-1851 |
| Spinks, Presley | Edgecombe (1); 39 acres, 1792 |
| Spinners Fork | Burke (1); 100 acres, 1799 |
| Spinns, James | Hawkins TN (1); 200 acres, 1794 |
| Spirads Creek | Surry (1); 100 acres, 1853 |
| Spire, James | Edgecombe (1); 400 acres, 1742 |
| Spire, John | Edgecombe (1); 640 acres, 1737 |
| Spirer, William | Wilkes (1); 100 acres, 1779 |
| Spires, John | Craven (1); 65 acres, 1789 |
| Spires, Robert | Chatham (1); 350 acres, 1779 |
| Spires, Theophilus | Guilford (1); 200 acres, 1782 |
| Spirit Branch | Orange (3); 875 acres, 1753-1759 |
| Spites, Thomas | Chowan (1); 640 acres, 1719 |
| Spites, William | Chowan (1); 400 acres, 1719 |
| Spiva, Aaron | Johnston (2); 300 acres, 1782 |
| Spiva, Jesse W. | Ashe (1); 100 acres, 1855 |
| Spiva, John | Ashe (2), Johnston (1); total 3 grants and 400 acres, 1782-1854 |
| Spiva, W. L. | Cherokee (1); 100 acres, 1877 |
| Spiva, William | Johnston (1); 200 acres, 1783 |
| Spivey Creek | Clay (1); 100 acres, 1883 |
| Spivey, A. W. | Clay (4), Macon (1); total 5 grants and 500 acres, 1875-1883 |
| Spivey, Aaron | Johnston (4), Bertie (1); total 5 grants and 670 acres, 1779-1803 |
| Spivey, B. J. | Buncombe (1); 0 acres, 1897 |
| Spivey, Benjamin | Chatham (2); 307 acres, 1804-1813 |
| Spivey, Benjamin W. | Moore (1); 0 acres, 1854 |
| Spivey, Caleb | Columbus (5), Dobbs (4); total 9 grants and 1299 acres, 1775-1881 |
| Spivey, Caleb, Jr. | Columbus (1); 100 acres, 1852 |
| Spivey, Calep | Glasgow (1); 400 acres, 1793 |
| Spivey, Daniel | Hertford (1); 640 acres, 1789 |
| Spivey, Edmond | Sampson (2), Duplin (1); total 3 grants and 450 acres, 1780-1787 |
| Spivey, Ephraim | Pitt (1); 100 acres, 1793 |
| Spivey, Ephram | Pitt (1); 100 acres, 1793 |
| Spivey, Francis | Edgecombe (2); 1023 acres, 1757 |
| Spivey, Franklin | Columbus (1); 100 acres, 1854 |
| Spivey, George | Columbus (1); 62 acres, 1852 |
| Spivey, J. J. | Columbus (1); 17 acres, 1891 |
| Spivey, James | Pitt (1); 100 acres, 1782 |
| Spivey, James R. | Columbus (3); 177 acres, 1853 |
| Spivey, Jesse | Moore (4), Columbus (1); total 5 grants and 353 acres, 1835-1854 |
| Spivey, Joab | Wayne (1); 100 acres, 1792 |
| Spivey, Joe | Moore (1); 0 acres, 1922 |
| Spivey, John | Johnston (4), Moore (1), Cherokee (1); total 6 grants and 410 acres, 1792-1855 |
| Spivey, John J. | Moore (1); 90 acres, 1854 |
| Spivey, John M. | Clay (1); 100 acres, 1883 |
| Spivey, Jonas | Buncombe (1); 50 acres, 1811 |
| Spivey, Jonathan | Bertie (2); 1200 acres, 1787 |
| Spivey, Littleton | Granville (4); 1369 acres, 1760 |
| Spivey, M. M. | Moore (2); 12 acres, 1858-1884 |
| Spivey, Moses | Rowan (1), Burke (1), Bertie (1); total 3 grants and 614 acres, 1761-1797 |
| Spivey, Nathaniel | Columbus (1); 200 acres, 1810 |
| Spivey, Watson | Clay (2), Cherokee (1); total 3 grants and 333 acres, 1851-1879 |
| Spivey, Watson G. | Clay (1); 300 acres, 1883 |
| Spivey, William | Columbus (3), Sampson (1), Johnston (1); total 5 grants and 244 acres, 1799-1871 |
| Spivey, William, Sr. | Columbus (1); 100 acres |
| Spivie, Thomas | Chowan (1); 316 acres, 1701 |
| Spivy, B. F. | Burke (1); 270 acres, 1881 |
| Spivy, Littleton | Granville (1); 600 acres, 1749 |
| Spivy, William, Sr. | Columbus (1); 100 acres, 1825 |
| Splacen, William | Rutherford (1); 125 acres, 1831 |
| Splaun, Peggey | Rutherford (1); 50 acres, 1815 |
| Splawn, Graham | Polk (1); 10 acres, 1861 |
| Splawn, H. G. | Rutherford (1); 8 acres, 1899 |
| Splawn, James | Rutherford (1); 150 acres, 1855 |
| Splitters Creek | Macon (1); 141 acres, 1839 |
| Spock, Jacob | Rowan (1); 24 acres, 1805 |
| Spoe, Charles | Granville (1); 175 acres, 1779 |
| Spofford, Samuel | Davidson (1); 0 acres, 1827 |
| Spoil Coney Creek | Johnston (6), Craven (1); total 7 grants and 1300 acres, 1757-1782 |
| Spookman, William | Sumner TN (1); 1000 acres, 1790 |
| Spooks Branch | Buncombe (1); 100 acres, 1797 |
| Spooks, Redman | Wilkes (1); 50 acres, 1850 |
| Spoon, Adam | Surry (1); 100 acres, 1784 |
| Spoon, Christian | Randolph (1); 50 acres, 1799 |
| Spoon, Eli | Randolph (1); 17 acres, 1847 |
| Spoon, John | Randolph (2); 110 acres, 1837-1845 |
| Spoon, W. D. | Randolph (1); 18 acres, 1901 |
| Spooner, Stanton | Onslow (6), New Hanover (1); total 7 grants and 578 acres, 1775-1834 |
| Spooners Bay | Onslow (3); 125 acres, 1804-1854 |
| Spooners Creek | Carteret (1); 140 acres, 1766 |
| Spoonhour, Henry | Surry (1), Stokes (1); total 2 grants and 600 acres, 1778-1798 |
| Spoonhour, Jacob | Stokes (1); 200 acres, 1797 |
| Spoonhour, Warner | Surry (1); 250 acres, 1783 |
| Spoonhour, Worner | Surry (1); 400 acres, 1778 |
| Spoons Creek | Orange (3); 303 acres, 1784-1819 |
| Spoonwater Creek | Caswell (2); 740 acres, 1784 |
| Spot | Currituck (1); 18 acres, 1839 |
| Spotted Branch | Moore (1); 49 acres, 1891 |
| Spout Branch | Burke (1); 50 acres, 1827 |
| Spradling, David | Burke (1); 50 acres |
| Spradling, James | Burke (3); 550 acres, 1790-1798 |
| Sprague, W. D. | Caldwell (2); 130 acres, 1875 |
| Sprague, Willaim D. | Caldwell (2); 767 acres, 1875 |
| Sprague, William | Caldwell (1); 150 acres, 1875 |
| Sprague, William D. | Caldwell (48); 17411 acres, 1873-1875 |
| Spraker, George | Rowan (2); 343 acres, 1793-1795 |
| Spralls, Solomon | Richmond (1); 24 acres, 1800 |
| Sprat, James | Anson (2), Mecklenburg (1); total 3 grants and 571 acres, 1794 |
| Sprathins, George | Surry (1); 20 acres, 1841 |
| Sprats, Thomas | Anson (1); 443 acres, 1753 |
| Spratt, Hugh | Lincoln (1); 12 acres, 1840 |
| Spratt, J. W. | Rutherford (1); 50 acres, 1864 |
| Spratt, James | Mecklenburg (7), Anson (1); total 8 grants and 431 acres, 1755-1815 |
| Spratt, Samuel | Rutherford (1), Burke (1); total 2 grants and 200 acres, 1817-1819 |
| Spratt, Thomas | Mecklenburg (1); 520 acres |
| Spratt, William | Lincoln (1); 31 acres, 1838 |
| Sprawling, Obidiah | Rutherford (1); 30 acres, 1802 |
| Sprawls, Elijah | Richmond (1); 50 acres, 1806 |
| Sprawls, Richard | Richmond (1); 5 acres, 1819 |
| Sprawls, Solomon | Richmond (4); 199 acres, 1794-1800 |
| Spray, Archibald | Mecklenburg (1); 4 acres, 1810 |
| Spreberry, John | Mecklenburg (1); 77 acres |
| Spree Island | Onslow (1); 5 acres, 1888 |
| Sprewell, James A. | Washington (1); 268 acres, 1888 |
| Sprewl, Aquilla | Davidson TN (1); 640 acres, 1789 |
| Sprewl, Richard | Davidson TN (1); 640 acres, 1789 |
| Spriggle, Martin | Burke (1); 251 acres, 1783 |
| Spriggs, Thomas | Tryon (2); 200 acres, 1779 |
| Spright, William | Wake (1), Craven (1); total 2 grants and 598 acres, 1775 |
| Spring Bay | Robeson (1); 75 acres, 1852 |
| Spring Branch | Bladen (14), New Hanover (13), Johnston (13), plus 98 grants in 30 other counties; total 138 grants and 19461 acres, 1739-1947 |
| Spring Branch Tract | Carteret (1); 100 acres, 1779 |
| Spring Cove | Buncombe (1); 100 acres, 1834 |
| Spring Creek | Buncombe (115), Madison (46), Bladen (12), plus 25 grants in 12 other counties; total 198 grants and 20900 acres, 1761-1907 |
| Spring Creek (tenn.) | Davidson TN (22), Sumner TN (21), Tennessee TN (20), plus 37 grants in 8 other counties; total 100 grants and 64243 acres, 1786-1802 |
| Spring Fork | Richmond (5), Anson (1), Chatham (1); total 7 grants and 561 acres, 1773-1852 |
| Spring Fork (tenn.) | Eastern District TN (4); 800 acres, 1794 |
| Spring Garden | Bertie (2); 640 acres, 1743 |
| Spring Garden Tract | Carteret (1); 200 acres, 1779 |
| Spring Hill Bottom | Onslow (1); 115 acres, 1859 |
| Spring Hill Township | Scotland (7), Richmond (5), Wilson (2); total 14 grants and 4047 acres, 1886-1920 |
| Spring Meadow | Bertie (2); 820 acres, 1723-1730 |
| Spring Mountain | Buncombe (2); 100 acres, 1811-1849 |
| Spring Pocosin | Bladen (1); 100 acres |
| Spring, Aaron | Beaufort (3); 600 acres, 1784 |
| Spring, John | Hyde (1); 160 acres, 1763 |
| Springer, Adam | Guilford (1); 14 acres, 1800 |
| Springer, D. W. | Stanly (1); 1 acres, 1912 |
| Springer, George | Montgomery (1); 200 acres |
| Springer, George W. H. | Stanly (1); 100 acres, 1845 |
| Springer, George, Jr. | Jackson (4); 1360 acres, 1895 |
| Springer, Leander D. | Ashe (1); 50 acres, 1873 |
| Springer, Lewis | Stanly (1); 100 acres, 1844 |
| Springer, Reuben | Stanly (2); 36 acres, 1846-1854 |
| Springer, Uriah | Orange (1); 272 acres, 1790 |
| Springfield | Anson (1), Guilford (1), Chowan (1); total 3 grants and 3070 acres, 1717-1752 |
| Springfield Tract | Carteret (1); 83 acres, 1779 |
| Springfield, George | Person (1); 100 acres, 1838 |
| Springfield, John | Person (1); 28 acres, 1827 |
| Springfield, Moses | Person (1); 150 acres, 1819 |
| Springfield, Richard | Person (1), Cumberland (1); total 2 grants and 300 acres, 1763-1858 |
| Springle, Elijah | Carteret (1); 48 acres, 1872 |
| Springle, G. W. | Carteret (1); 660 acres, 1880 |
| Springle, William | Beaufort (1); 300 acres |
| Springles, W. D. | Haywood (1); 640 acres |
| Springs Creek | Cherokee (1); 100 acres, 1854 |
| Springs, Alexander | Mecklenburg (1); 25 acres, 1850 |
| Springs, John | Mecklenburg (2), Lincoln (1), Hyde (1); total 4 grants and 3350 acres, 1763-1805 |
| Springs, Sophiah | Mecklenburg (1); 25 acres, 1820 |
| Springs, William P. | Mecklenburg (1); 110 acres, 1821 |
| Sprinkle, George | Surry (1), Stokes (1); total 2 grants and 400 acres, 1789-1796 |
| Sprinkle, Joseph | Surry (1); 14 acres, 1879 |
| Sprinkle, Michael | Surry (1), Stokes (1); total 2 grants and 230 acres, 1779-1811 |
| Sprinkle, Peter | Surry (1); 50 acres, 1795 |
| Sprinkle, Samuel | Wilkes (1); 15 acres, 1858 |
| Sprinkle, Thomas | Surry (1); 13 acres, 1872 |
| Sprinkle, William | Buncombe (1); 100 acres, 1830 |
| Sprinkler, George | Surry (1); 230 acres, 1780 |
| Sprinkler, W. D. | Haywood (1); 300 acres, 1890 |
| Sprite, Henry | Sullivan TN (1); 466 acres, 1793 |
| Sproatts, William | Lincoln (1); 11 acres, 1848 |
| Sprodling, David | Burke (1); 100 acres, 1798 |
| Sprodling, James | Burke (1); 50 acres, 1801 |
| Sproll, Solomon | Richmond (1); 400 acres, 1790 |
| Sprot, Whiton | Anson (1); 250 acres, 1758 |
| Sprote, James | Anson (2); 500 acres, 1754 |
| Sproth, James | Mecklenburg (1); 130 acres, 1766 |
| Sprots, Thomas | Anson (2); 1400 acres, 1753 |
| Sprott, Andrew | Mecklenburg (1); 34 acres, 1769 |
| Sprott, James | Anson (2); 800 acres, 1762 |
| Sprott, Thomas | Anson (3), Knox TN (1); total 4 grants and 2240 acres, 1762-1802 |
| Sprout Branch | Buncombe (1); 20 acres, 1840 |
| Sprout, John | Hawkins TN (1); 200 acres |
| Sprout, William | Guilford (1), Cumberland (1); total 2 grants and 479 acres, 1771-1784 |
| Sprowels Ferry | Cumberland (1); 500 acres, 1772 |
| Sprowl, William | Cumberland (3); 350 acres, 1768-1791 |
| Sprowls, William | Cumberland (2); 200 acres, 1783-1791 |
| Spruce Branch | McDowell (1), Burke (1); total 2 grants and 92 acres, 1830-1858 |
| Spruce Fork | Buncombe (2); 50 acres, 1831-1833 |
| Spruce, John D. | Cumberland (1); 5 acres, 1854 |
| Spruce, John Hankin | Guilford (1); 140 acres, 1796 |
| Spruce, John Hawkins | Guilford (1); 200 acres, 1794 |
| Spruce, William | Guilford (3), Rowan (1), Craven (1); total 5 grants and 746 acres, 1757-1803 |
| Spruel, Samuel, Jr. | Tyrrell (1); 640 acres |
| Spruill Fork | Tyrrell (1); 100 acres, 1795 |
| Spruill, Benjamin | Tyrrell (9); 2208 acres, 1779-1852 |
| Spruill, C. | Robertson TN (1); 640 acres |
| Spruill, Charles | Tyrrell (1); 10 acres |
| Spruill, E. R. | Washington (1); 1 acres, 1894 |
| Spruill, Ebenezer | Tyrrell (2); 213 acres, 1783-1797 |
| Spruill, Evan | Tyrrell (1); 299 acres, 1784 |
| Spruill, Godfrey | Chowan (2); 1136 acres, 1713 |
| Spruill, Godfrey, Jr. | Chowan (1); 180 acres, 1714 |
| Spruill, Hezehiah G. | Tyrrell (1); 50 acres, 1839 |
| Spruill, Hezekiah | Tyrrell (10); 2687 acres, 1784-1838 |
| Spruill, Hezikiah | Tyrrell (1); 100 acres, 1786 |
| Spruill, Hezkiah | Tyrrell (1); 97 acres, 1836 |
| Spruill, J. A. | Washington (1); 1004 acres, 1889 |
| Spruill, J. W. | Tyrrell (1); 44 acres, 1905 |
| Spruill, James | Tyrrell (1); 6 acres, 1802 |
| Spruill, John | Tyrrell (1); 101 acres, 1759 |
| Spruill, Joseph | Tyrrell (9); 3766 acres, 1742-1801 |
| Spruill, Joseph A. | Tyrrell (1), Bertie (1); total 2 grants and 308 acres, 1844 |
| Spruill, Joseph, Jr. | Tyrrell (1); 640 acres, 1784 |
| Spruill, Joseph, Sr. | Tyrrell (1); 202 acres, 1742 |
| Spruill, King | Tyrrell (1); 180 acres, 1795 |
| Spruill, Nehemiah | Tyrrell (5); 869 acres, 1779-1791 |
| Spruill, Samuel | Tyrrell (4); 639 acres, 1743-1835 |
| Spruill, Samuel, Jr. | Tyrrell (2); 820 acres, 1753 |
| Spruill, Stephen | Tyrrell (2); 400 acres, 1786 |
| Spruill, Thomas | Tyrrell (2); 277 acres, 1779-1798 |
| Spruill, Thomas Harkins | Tyrrell (1); 75 acres, 1780 |
| Spruill, William | Tyrrell (1); 600 acres, 1786 |
| Spruit, John | Rutherford (1); 100 acres, 1799 |
| Sprutt, John | Tyrrell (1); 230 acres, 1782 |
| Sprutts, Thomas | Anson (1); 443 acres, 1753 |
| Spuir, William | Wilkes (1); 100 acres, 1789 |
| Spuirland, Zachariah | Ashe (1); 100 acres, 1801 |
| Spure, John | Tyrrell (1); 300 acres, 1742 |
| Spurgeon Creek | Rowan (1), Davidson (1); total 2 grants and 39 acres, 1811-1823 |
| Spurgeon, John | Greene TN (1); 100 acres, 1787 |
| Spurgin, Janet | Rowan (1); 400 acres, 1792 |
| Spurgin, John | Sullivan TN (1); 194 acres, 1797 |
| Spurgin, William | Sullivan TN (2), Greene TN (1); total 3 grants and 1150 acres, 1789-1790 |
| Spurlin, D. S. | Alleghany (1); 21 acres, 1874 |
| Spurlin, Daniel | Ashe (1), Wilkes (1); total 2 grants and 131 acres, 1854-1856 |
| Spurlin, Daniel A. | Alleghany (1); 390 acres, 1872 |
| Spurlin, Deblok | Ashe (1); 200 acres, 1811 |
| Spurlin, Elias | Alleghany (1); 63 acres, 1877 |
| Spurlin, Elijah | Lincoln (2); 109 acres, 1802-1835 |
| Spurlin, Ira | Alleghany (1); 25 acres, 1875 |
| Spurlin, Isaac, Jr. | Cleveland (1); 11 acres, 1843 |
| Spurlin, Matthew | Rutherford (1); 37 acres, 1855 |
| Spurlin, Talitha | Swain (1); 100 acres, 1891 |
| Spurlin, William | Wilkes (2), Ashe (1); total 3 grants and 240 acres, 1856 |
| Spurlin, Zachariah | Ashe (2); 400 acres, 1801-1811 |
| Spurling, John | Ashe (1); 100 acres, 1838 |
| Spurling, John, Jr. | Ashe (1); 50 acres, 1839 |
| Spurling, William | Chatham (3); 506 acres, 1780-1797 |
| Spurling, Zachariah | Surry (2), Ashe (2); total 4 grants and 367 acres, 1789-1820 |
| Spurling, Zachariah, Sr. | Ashe (1); 100 acres, 1809 |
| Spurlock, John | Surry (1); 200 acres, 1780 |
| Spurr, Spencer | Sumner TN (1); 640 acres, 1791 |
| Spurrier, John | Rockingham (1); 50 acres, 1804 |
| Spurs, John | Bertie (1); 300 acres, 1723 |
| Spurtin Family | Wilkes (1); 100 acres, 1798 |
| Spyser, Elijah | New Hanover (1); 200 acres |
| Squairs, Hugh H. | Clay (2); 1280 acres, 1876 |
| Squalling Ponds | Johnston (1); 100 acres, 1790 |
| Squaran Swamp | Chowan (1); 640 acres, 1720 |
| Squaw Branch | Rutherford (2), Swain (1); total 3 grants and 121 acres, 1883-1894 |
| Squior, John | New Hanover (1); 100 acres, 1756 |
| Squire Swamp | Bertie (1); 80 acres, 1788 |
| Squire, Appleton | Beaufort (2); 150 acres, 1800 |
| Squire, John | Tryon (1), New Hanover (1); total 2 grants and 400 acres, 1760 |
| Squire, Sarah | Beaufort (1); 300 acres |
| Squires Branch | Onslow (3); 359 acres, 1816-1880 |
| Squires Creek | Onslow (1); 15 acres, 1816 |
| Squires, Appleton | Beaufort (1); 100 acres, 1798 |
| Squires, Boaz | Craven (1); 150 acres, 1767 |
| Squires, James | Bladen (4), Alamance (1); total 5 grants and 1256 acres, 1817-1881 |
| Squires, John | New Hanover (4), Bladen (2), Tennessee TN (1); total 7 grants and 1760 acres, 1740-1797 |
| Squires, John H. | New Hanover (1); 80 acres, 1871 |
| Squires, Joseph S. | Caldwell (1); 21 acres, 1904 |