| South Fork Catawba River | Lincoln (302), Burke (157), Mecklenburg (124), plus 57 grants in 4 other counties; total 640 grants and 147485 acres, 1755-1921 |
| South Fork Country Line Creek | Caswell (1); 72 acres, 1802 |
| South Fork Creek | Tyrrell (3); 525 acres, 1779-1789 |
| South Fork Crooked Creek | Mecklenburg (1); 300 acres, 1773 |
| South Fork Flat Creek | Macon (2), Buncombe (2); total 4 grants and 201 acres, 1797-1853 |
| South Fork Jones Creek | Anson (18); 2081 acres, 1775-1811 |
| South Fork Little River | Orange (9); 2873 acres, 1761-1788 |
| South Fork Mountain Creek | Burke (2); 900 acres, 1782 |
| South Fork Muddy Creek | Burke (3); 300 acres, 1794-1818 |
| South Fork New River | Ashe (602); 45632 acres, 1755-1927 |
| South Fork River | Burke (1); 50 acres, 1856 |
| South Fork Tar River | Caswell (2); 1330 acres, 1782 |
| South Fork Upper Creek | Burke (39); 5670 acres, 1780-1838 |
| South Fork Yadkin River | Iredell (1); 100 acres, 1794 |
| South Fourteenth Street | Carteret (1); 0 acres, 1956 |
| South Harper Creek | Burke (1); 25 acres, 1838 |
| South Harpeth (tenn.) | Davidson TN (1); 640 acres, 1793 |
| South Harpeth River (tenn.) | Davidson TN (41); 26546 acres, 1793-1797 |
| South Hico Creek | Granville (1); 211 acres, 1753 |
| South Hominy Creek | Burke (2); 500 acres, 1790 |
| South Hyco | Caswell (2); 206 acres, 1779-1801 |
| South Hyco Creek | Caswell (76), Orange (15), Person (1); total 92 grants and 24646 acres, 1755-1812 |
| South Hyco River | Person (2); 33 acres, 1810-1819 |
| South Johns Parish | Pasquotank (1); 225 acres, 1761 |
| South Lake | Tyrrell (5); 684 acres, 1818-1853 |
| South Lancaster | Chowan (3), Carteret (1); total 4 grants and 1800 acres, 1714-1747 |
| South Lower River | Burke (1); 100 acres, 1810 |
| South Mill Creek | Buncombe (1); 176 acres, 1811 |
| South Mills | Currituck (3); 1231 acres, 1782-1789 |
| South Mountains | Burke (7); 1891 acres, 1790-1904 |
| South Muddy Creek | Burke (110), McDowell (62); total 172 grants and 20229 acres, 1779-1900 |
| South Pacolet River | Tryon (1), Rutherford (1); total 2 grants and 500 acres, 1772-1783 |
| South Pine Island | Currituck (1); 263 acres, 1783 |
| South Point Township | Gaston (1); 4 acres, 1903 |
| South Prong | Cumberland (1); 100 acres, 1817 |
| South River | Bladen (311), Sampson (124), New Hanover (101), plus 145 grants in 10 other counties; total 681 grants and 123999 acres, 1716-1924 |
| South Roundabout | Wayne (1); 50 acres, 1790 |
| South Swamp | Beaufort (1); 640 acres, 1737 |
| South Toe River | Yancey (150), Burke (58), Buncombe (4); total 212 grants and 135642 acres, 1791-1941 |
| South Toe Township | Yancey (37); 1841 acres, 1820-1939 |
| South Turkey Creek | Buncombe (21), Burke (3); total 24 grants and 3487 acres, 1789-1886 |
| South Upper Creek | Burke (1); 50 acres, 1819 |
| South Washington | New Hanover (2); 107 acres, 1844 |
| South West | Craven (1); 100 acres, 1763 |
| South West Creek | Anson (1); 100 acres, 1786 |
| South West District | Onslow (1); 56 acres, 1860 |
| South Yadkin | Iredell (3); 890 acres, 1792-1794 |
| South Yadkin Creek | Iredell (1); 216 acres, 1797 |
| South Yadkin River | Rowan (185), Iredell (150), Alexander (59), plus 2 grants in 2 other counties; total 396 grants and 83713 acres, 1755-1909 |
| South, Benjamin | Caswell (1); 63 acres, 1784 |
| South, Britten | Watauga (1); 100 acres, 1854 |
| South, Daniel | Ashe (1); 100 acres, 1838 |
| South, Eli | Ashe (9), Watauga (1); total 10 grants and 523 acres, 1820-1852 |
| South, Eli, Jr. | Watauga (1); 100 acres, 1850 |
| South, Eli, Sr. | Ashe (1), Watauga (1); total 2 grants and 200 acres, 1840-1850 |
| South, Enoch, Sr. | Watauga (1); 17 acres, 1900 |
| South, John | Surry (1), Ashe (1); total 2 grants and 150 acres, 1840-1846 |
| South, Samuel | Watauga (1); 100 acres, 1854 |
| Southall, John W. | Hertford (1); 563 acres, 1839 |
| Southampton County (va.) | Northampton (1); 109 acres, 1779 |
| Southard, Andrew | Hawkins TN (1); 270 acres, 1793 |
| Southard, Isaac | Surry (4); 250 acres, 1783-1804 |
| Southard, Levi W. | Surry (1); 30 acres, 1840 |
| Southard, M. A. | Surry (1); 2 acres, 1902 |
| Southard, Martin | Surry (3); 450 acres, 1824-1833 |
| Southard, William | Caswell (1); 400 acres, 1783 |
| Souther, Henry | Wilkes (3); 170 acres, 1810-1817 |
| Souther, J. M. | Wilkes (1); 24 acres, 1899 |
| Souther, James | McDowell (1); 100 acres, 1848 |
| Souther, James M. | Wilkes (1); 130 acres, 1895 |
| Souther, John | Burke (1), Wilkes (1); total 2 grants and 190 acres, 1782 |
| Souther, Joseph | Wilkes (1); 47 acres, 1890 |
| Souther, Joshua | Wilkes (4); 179 acres, 1808-1818 |
| Souther, Lucinda | McDowell (1); 172 acres, 1873 |
| Souther, Nancy | McDowell (3); 204 acres, 1873-1924 |
| Souther, Noah | McDowell (16); 1859 acres, 1850-1890 |
| Souther, Noah, and Co. | McDowell (1); 300 acres, 1861 |
| Souther, Stephen | Burke (1), Wilkes (1); total 2 grants and 300 acres, 1782-1818 |
| Souther, W. J. | McDowell (1); 60 acres, 1873 |
| Souther, William J. | McDowell (1); 56 acres, 1864 |
| Souther, Willington | Wilkes (2); 200 acres, 1838 |
| Souther,joshua | Wilkes (1); 50 acres, 1808 |
| Southerd, Micajoh | Lincoln (1); 80 acres, 1801 |
| Southerlain Boardtree Branch | Wilkes (1); 50 acres, 1808 |
| Southerland, Alexander | Granville (1); 880 acres, 1756 |
| Southerland, Alsa | Duplin (1); 33 acres, 1846 |
| Southerland, Daniel | Duplin (7), Surry (1), New Hanover (1); total 9 grants and 1313 acres, 1788-1813 |
| Southerland, Daniel, Sr. | Duplin (1); 77 acres, 1831 |
| Southerland, David | Duplin (2), Hawkins TN (1), Wilkes (1); total 4 grants and 536 acres, 1779-1836 |
| Southerland, George | Macon (1), Tennessee TN (1), Sumner TN (1), plus 1 grant in 1 other county; total 4 grants and 1654 acres, 1788-1851 |
| Southerland, Green B. | Person (1); 10 acres, 1854 |
| Southerland, J. F. | Onslow (1); 15 acres, 1892 |
| Southerland, James | Edgecombe (1), Tennessee TN (1); total 2 grants and 294 acres, 1793-1816 |
| Southerland, Jane | Macon (2); 100 acres, 1883 |
| Southerland, Jesse B. | Duplin (1); 73 acres, 1848 |
| Southerland, John | Duplin (4), Guilford (2), Haywood (1), plus 2 grants in 2 other counties; total 9 grants and 1425 acres, 1782-1882 |
| Southerland, John H. | Graham (1); 6880 acres, 1892 |
| Southerland, Joseph | Ashe (3); 111 acres, 1830-1838 |
| Southerland, Mordicai | Burke (1); 150 acres, 1803 |
| Southerland, Philip | Duplin (2); 250 acres, 1785-1801 |
| Southerland, Phill | Duplin (2); 170 acres, 1793-1806 |
| Southerland, Phillip | Stokes (1); 100 acres, 1798 |
| Southerland, Ransom | Randolph (1); 300 acres, 1785 |
| Southerland, Robert | Duplin (3); 328 acres, 1784-1809 |
| Southerland, Thomas | Ashe (1); 200 acres, 1875 |
| Southerland, William | Duplin (3), Halifax (1), Davidson TN (1); total 5 grants and 824 acres, 1757-1793 |
| Southerlands Marsh | Duplin (1); 190 acres, 1769 |
| Southerlin, David | Duplin (1), Hawkins TN (1); total 2 grants and 351 acres, 1791-1830 |
| Southerlin, Thomas | Ashe (1); 62 acres, 1817 |
| Southerlin, Wells | New Hanover (1); 12 acres, 1857 |
| Southern Branch | Pasquotank (1); 16 acres, 1791 |
| Southern Mountain | Wilkes (1); 100 acres, 1788 |
| Southern, Boaz | Stokes (2); 100 acres, 1797 |
| Southern, Calvin J. | Stokes (1); 29 acres, 1890 |
| Southern, J. Calvin | Stokes (1); 202 acres, 1891 |
| Southern, James | Stokes (1), Washington TN (1); total 2 grants and 332 acres, 1784-1856 |
| Southern, Michael | Burke (1); 30 acres, 1802 |
| Southern, Noah | Yancey (5); 2222 acres, 1881-1886 |
| Southern, Reuben | Stokes (2); 145 acres, 1851-1863 |
| Southern, Reubin | Guilford (1); 100 acres, 1782 |
| Southern, William | Surry (1); 100 acres, 1789 |
| Southern, William B. | Stokes (1); 31 acres, 1876 |
| Southern, William C. | Stokes (1); 32 acres, 1856 |
| Southers Family | Wilkes (1); 21 acres, 1853 |
| Southport | Brunswick (31); 239 acres, 1848-1893 |
| Southward, William | Burke (1); 370 acres, 1784 |
| Southwest Creek | Onslow (175), Dobbs (91), Craven (75), plus 49 grants in 4 other counties; total 390 grants and 93952 acres, 1736-1895 |
| Southwest Prong | Craven (1); 20 acres, 1829 |
| Southwest River | Craven (1); 100 acres, 1763 |
| Southword, Levi | Surry (1); 58 acres, 1838 |
| Soutwest Creek | Dobbs (1); 400 acres, 1764 |
| Sovereign Creek | Hyde (4); 598 acres, 1720-1743 |
| Sow Island | Pamlico (1); 8 acres, 1929 |
| Soward, Absolam | Anson (1); 150 acres, 1783 |
| Soward, Daniel | Anson (1); 100 acres |
| Sowards, Absalam | Anson (2); 400 acres, 1783 |
| Sowel, Charles | Bertie (1); 166 acres, 1787 |
| Sowel, Isaac | Moore (1); 220 acres, 1818 |
| Sowel, Jesse | Moore (1); 50 acres |
| Sowel, Joseph, Sr. | Bladen (1); 640 acres, 1735 |
| Sowel, Samuel | Duplin (3); 381 acres, 1792-1799 |
| Sowell Run | Johnston (2); 600 acres, 1755 |
| Sowell, Aaron A. | Moore (1); 7 acres, 1843 |
| Sowell, Charles | Moore (2); 90 acres, 1805-1821 |
| Sowell, Dempsey | Moore (1); 16 acres, 1830 |
| Sowell, Eli R. | Moore (2); 19 acres, 1843-1858 |
| Sowell, James | Bertie (1); 130 acres, 1786 |
| Sowell, Jesse | Moore (2); 58 acres, 1806-1820 |
| Sowell, John | Moore (1), Montgomery (1); total 2 grants and 139 acres, 1828 |
| Sowell, Joshua L. | Moore (1); 48 acres, 1849 |
| Sowell, Lewis | Moore (1), Davidson TN (1); total 2 grants and 670 acres, 1796 |
| Sowell, Lucias | Moore (1); 30 acres |
| Sowell, Richard | Chowan (1); 400 acres, 1712 |
| Sowell, Samuel | Duplin (4); 836 acres, 1785-1808 |
| Sowell, W. F. | Moore (1); 75 acres, 1855 |
| Sowers, Christiana | Rowan (1); 100 acres, 1792 |
| Sowers, George | Mecklenburg (1); 200 acres, 1787 |
| Sowers, Isaac | Rowan (2); 400 acres, 1784 |
| Sowers, John | Rowan (1); 200 acres, 1789 |
| Sowers, Philip | Rowan (1); 300 acres, 1789 |
| Sowers, Valentine | Rowan (2); 262 acres, 1792-1806 |
| Sowl, Joseph, Sr. | Columbus (1); 50 acres, 1845 |
| Sowl, Silvanus | New Hanover (1); 400 acres |
| Sowles, Isham | Columbus (1); 50 acres, 1858 |
| Sowles, Nathaniel | Brunswick (1); 200 acres |
| Sowls, Benjamin | Columbus (1); 100 acres, 1836 |
| Sowls, Carlton | Columbus (1); 100 acres, 1863 |
| Sowls, Isham | Columbus (5); 400 acres, 1835-1853 |
| Sowls, Jesse | Columbus (1); 100 acres, 1863 |
| Sowls, Joseph | Columbus (1); 50 acres, 1840 |
| Sowls, Joseph G. | Columbus (1); 8 acres, 1850 |
| Sowls, Joshua | Columbus (1), Bladen (1); total 2 grants and 175 acres, 1802-1830 |
| Sowls, Miriam | Columbus (1); 100 acres, 1863 |
| Sowls, N. | Columbus (1); 100 acres |
| Sowls, Nathaniel | Columbus (2), Brunswick (1); total 3 grants and 400 acres, 1798-1838 |
| Sowls, Nathaniel, Jr. | Columbus (1); 100 acres |
| Sowsley, Samuel | Nash (1); 105 acres, 1782 |
| Spack, Gottlick | Stokes (1); 400 acres, 1795 |
| Spacys Ridge | Caldwell (1); 28 acres, 1899 |
| Spafford, Samuel | Davidson (1); 3 acres, 1834 |
| Spaight, Christian | Lincoln (1); 270 acres, 1805 |
| Spaight, Jessee | Greene TN (1); 100 acres, 1795 |
| Spaight, Richard | Anson (38), Craven (12), Dobbs (4), plus 4 grants in 3 other counties; total 58 grants and 23036 acres, 1755-1762 |
| Spaight, Richard Dobbs | Jones (5), Craven (2), Brunswick (1); total 8 grants and 2128 acres, 1795-1858 |
| Spaight, Richard Dobbs, Sr. | Craven (32); 37424 acres, 1787-1801 |
| Spaight, William | Craven (3), Johnston (1); total 4 grants and 795 acres, 1760-1764 |
| Spain, Augustain | Anson (1); 50 acres, 1801 |
| Spain, Augustine | Hyde (2), Anson (1); total 3 grants and 1150 acres, 1786-1799 |
| Spain, Augustus | Hyde (1); 35 acres, 1900 |
| Spain, Austin | Sumner TN (1); 428 acres, 1793 |
| Spain, Drewry | Pitt (2); 150 acres, 1790 |
| Spain, Eps | Sumner TN (1); 1000 acres, 1793 |
| Spain, Frederick | Wake (2); 1240 acres, 1780 |
| Spain, James P. | Pamlico (1); 15 acres, 1904 |
| Spain, John | Wake (1); 300 acres, 1782 |
| Spain, Seaborn | Buncombe (1); 80 acres, 1832 |
| Spain, Thomas | Pitt (2), Sumner TN (1); total 3 grants and 1150 acres, 1790-1793 |
| Spain, William | Sumner TN (1); 1000 acres, 1793 |
| Spaine, John | Bertie (1); 160 acres, 1725 |
| Spainhour, Henry | Surry (2); 250 acres, 1783-1784 |
| Spainhour, Jacob | Stokes (2); 123 acres, 1799-1800 |
| Spainhour, Michael | Burke (1); 66 acres, 1854 |
| Spainhour, Warner | Surry (2); 500 acres, 1783 |
| Spainhower, Michael | Burke (1); 92 acres, 1857 |
| Spalden, Benjamin | Columbus (1); 10 acres, 1854 |
| Spalden, Emanuel | Columbus (1); 10 acres, 1854 |
| Spalding, Armstead | Columbus (2); 135 acres, 1840-1847 |
| Spalding, Benjamin | Columbus (9); 735 acres, 1832-1851 |
| Spalding, Charles | Granville (1); 128 acres, 1787 |
| Spalding, Edmond | Sumner TN (1); 640 acres, 1793 |
| Spalding, Edmond, Jr. | Sumner TN (1); 640 acres, 1793 |
| Spalding, Emanuel | Columbus (2); 87 acres, 1842-1848 |
| Spalding, Immanuel | Columbus (1); 100 acres, 1836 |
| Spalding, William | Columbus (1); 50 acres, 1846 |
| Spaldwin, Emmanuel | Columbus (1); 50 acres, 1852 |
| Spaldwin, Iver | Bladen (2); 117 acres, 1847-1848 |
| Span, John | Edgecombe (2); 1200 acres, 1730-1737 |
| Span, Rubin | Watauga (1); 10 acres, 1904 |
| Span, William | Rutherford (1); 45 acres, 1797 |
| Spangler, Jacob | Lincoln (1); 37 acres, 1810 |
| Spangler, Washington | Surry (1); 27 acres, 1854 |
| Spaniel, Joseph A. | Bertie (1); 480 acres, 1850 |
| Spanish Oak Branch | Wilkes (1); 50 acres, 1827 |
| Spankler, Peter | Lincoln (1); 200 acres, 1795 |
| Spann, Charles | Dobbs (1); 200 acres, 1783 |
| Spann, James | Davidson TN (1); 228 acres, 1788 |
| Spann, John | Buncombe (1); 48 acres, 1837 |
| Spann, William | Rutherford (1); 73 acres, 1802 |
| Spann, Willis | Tennessee TN (2), Halifax (1); total 3 grants and 1044 acres, 1791-1793 |
| Spans Creek | Rowan (1); 491 acres, 1762 |
| Spar, Henry | Sullivan TN (1); 200 acres, 1787 |
| Sparger, Henry | Surry (2); 400 acres, 1820-1826 |
| Sparger, J. B. | Surry (1); 20 acres, 1911 |
| Sparger, John | Surry (2); 250 acres, 1815 |
| Sparger, John, Sr. | Surry (1); 100 acres, 1818 |
| Sparger, Marlin | Surry (1); 17 acres, 1848 |
| Sparger, Murlin | Surry (5); 662 acres, 1854-1877 |
| Spark Creek | Wilkes (1); 3 acres, 1875 |
| Spark, Thomas | Burke (1); 100 acres, 1831 |
| Sparkes Creek | Wilkes (1); 50 acres, 1821 |
| Sparkes, Allen | Burke (1); 150 acres, 1836 |
| Sparkes, Burrell | Johnston (1); 100 acres, 1782 |
| Sparkes, Calvin | Rutherford (1); 90 acres, 1848 |
| Sparkes, George | Surry (1); 100 acres, 1825 |
| Sparkes, Hardin | Yancey (2); 68 acres, 1846-1852 |
| Sparkes, James | Burke (2); 125 acres, 1834-1836 |
| Sparkes, Jonas | Wilkes (1); 25 acres, 1836 |
| Sparkes, Jonothan | Wilkes (1); 50 acres, 1835 |
| Sparkes, Matthew | Wilkes (1); 400 acres, 1779 |
| Sparkes, Reuben J. | Wilkes (1); 100 acres, 1854 |
| Sparkes, Robert | Wilkes (1); 17 acres, 1854 |
| Sparkes, Solomon | Wilkes (1); 35 acres, 1847 |
| Sparkes, Timothy | Wilkes (1); 27 acres, 1856 |
| Sparkes, Watson | Yancey (1); 25 acres, 1858 |
| Sparkes, William R. | Wilkes (1); 25 acres, 1836 |
| Sparkes, Wilson | Yancey (1); 42 acres, 1855 |
| Sparkman | Onslow (1); 8 acres, 1843 |
| Sparkman, Charney | Onslow (4); 343 acres, 1824-1835 |
| Sparkman, Chorina | Onslow (1); 8 acres, 1843 |
| Sparkman, Edward | New Hanover (1), Tennessee TN (1), Davidson TN (1); total 3 grants and 1280 acres, 1784-1789 |
| Sparkman, Isaiah | Davidson TN (1); 640 acres, 1787 |
| Sparkman, Jesse | Tyrrell (2), Bertie (1); total 3 grants and 1495 acres, 1789 |
| Sparkman, Thomas | Martin (1); 300 acres, 1804 |
| Sparkman, William | Bertie (3), Tennessee TN (1), Davidson TN (1); total 5 grants and 1606 acres, 1755-1800 |
| Sparkman, William R. | Bertie (1); 73 acres |
| Sparks Creek | Rowan (6), Wilkes (3); total 9 grants and 2702 acres, 1761-1884 |
| Sparks, A. J. | Alleghany (1); 32 acres, 1875 |
| Sparks, Allen | Yancey (2); 80 acres, 1836 |
| Sparks, Amanuel | Wilkes (1); 53 acres, 1849 |
| Sparks, Amanuel W. | Wilkes (1); 47 acres, 1857 |
| Sparks, Benjamin | Surry (4); 900 acres |
| Sparks, Calvin | Rutherford (5); 419 acres, 1847-1850 |
| Sparks, Daniel | Wilkes (1); 100 acres, 1856 |
| Sparks, Emanuel | Wilkes (3), Ashe (1); total 4 grants and 243 acres, 1848-1857 |
| Sparks, Ephraim | Ashe (1); 100 acres, 1814 |
| Sparks, George | Surry (1); 31 acres, 1818 |
| Sparks, Harden | Yancey (1); 50 acres, 1849 |
| Sparks, Hardy | Ashe (1); 100 acres, 1824 |
| Sparks, Hugh | Wilkes (1); 12 acres, 1850 |
| Sparks, J. E. | Alleghany (1); 30 acres, 1898 |
| Sparks, James | Burke (4), Wilkes (3); total 7 grants and 347 acres, 1828-1871 |
| Sparks, James P. | Wilkes (1); 100 acres, 1849 |
| Sparks, Jeremiah | Burke (5), Yancey (2); total 7 grants and 425 acres, 1820-1836 |
| Sparks, Joel | Wilkes (4); 212 acres, 1811-1850 |
| Sparks, John | Wilkes (3); 400 acres, 1785-1835 |
| Sparks, John, Jr. | Wilkes (1); 30 acres, 1829 |
| Sparks, John, Sr. | Wilkes (1); 50 acres, 1804 |
| Sparks, Jones | Rowan (1); 204 acres, 1786 |
| Sparks, Joseph | Surry (1), Wilkes (1); total 2 grants and 300 acres, 1782-1806 |
| Sparks, Levi | Wilkes (2); 200 acres, 1806-1809 |
| Sparks, Martha | Rowan (1); 372 acres, 1761 |
| Sparks, Mary | Wilkes (1); 9 acres, 1880 |
| Sparks, Mathew | Yancey (2); 150 acres, 1836-1851 |
| Sparks, Matthew | Surry (4), Yancey (2), Ashe (1); total 7 grants and 962 acres, 1780-1856 |
| Sparks, Matthias | Greene TN (1); 400 acres, 1788 |
| Sparks, R. J. | Wilkes (1); 35 acres, 1860 |
| Sparks, Richmond | Wilkes (2); 60 acres, 1842 |
| Sparks, Robert | Bladen (1), Wilkes (1); total 2 grants and 400 acres, 1746-1849 |
| Sparks, S. A. | Wilkes (1); 2 acres, 1913 |
| Sparks, Salomon | Rowan (2); 541 acres, 1761-1762 |
| Sparks, Samuel | Washington TN (1); 50 acres, 1786 |
| Sparks, Samuel B. | Cherokee (1), Yancey (1); total 2 grants and 264 acres, 1856-1859 |
| Sparks, Thomas | Guilford (2), Surry (1), Cumberland (1), plus 1 grant in 1 other county; total 5 grants and 1254 acres, 1774-1850 |
| Sparks, Thomas M. | Yancey (5); 255 acres, 1838-1860 |
| Sparks, William | Surry (4), Wilkes (2); total 6 grants and 825 acres, 1787-1835 |
| Sparks, William R. | Wilkes (2); 73 acres, 1832-1859 |
| Sparks, William S. | Surry (1); 250 acres, 1818 |
| Sparks, William, Jr. | Surry (2); 450 acres, 1782-1787 |
| Sparks, Wilson | Mitchell (2); 100 acres, 1875-1880 |
| Sparks, Zeb | Mitchell (1); 5 acres, 1907 |
| Sparman, Edward | Sampson (1); 28 acres, 1809 |
| Sparrow, Gedion | Craven (1); 44 acres, 1811 |
| Sparrow, John | Orange (1); 330 acres, 1784 |
| Sparrow, Joshua | Pasquotank (2); 403 acres, 1714 |
| Sparrow, Paul | Craven (3); 1300 acres, 1775-1809 |
| Sparrow, Samuel | Craven (2); 12 acres, 1804 |
| Sparrow, Thomas | Craven (3); 52 acres, 1798-1824 |
| Sparrow, Thomas Case | Buncombe (1); 50 acres, 1838 |
| Sparrow, William | Craven (1); 229 acres, 1808 |
| Sparrow, William S. | Craven (3); 706 acres, 1809-1816 |
| Spats, Henry | Surry (1); 200 acres, 1807 |
| Spaugh, Adam | Rowan (2); 420 acres, 1785-1787 |
| Spaughs Creek | Rowan (1); 280 acres, 1785 |
| Spaulden, Armsted | Columbus (1); 19 acres, 1853 |
| Spaulden, Henry | Granville (1); 40 acres, 1780 |
| Spaulden, John | Bladen (1); 2 acres, 1853 |
| Spauldin, Edward | Sumner TN (1); 640 acres, 1793 |
| Spaulding, Benjamin | Columbus (1); 60 acres, 1833 |
| Spaulding, David | Columbus (1); 20 acres, 1860 |
| Spaulding, Jonathan | Columbus (1); 9 acres |
| Spaulding, McIver | Columbus (1); 9 acres |
| Spaw, Henry | Hawkins TN (1); 200 acres, 1794 |
| Speace, J. L. | Yadkin (1); 25 acres |
| Speagel, Samuel | Lincoln (1); 70 acres |
| Speagial, Martin | Lincoln (1); 150 acres, 1795 |
| Speagil, Martin | Lincoln (1); 40 acres, 1795 |
| Speagle, Martin | Lincoln (2), Burke (1); total 3 grants and 450 acres, 1782-1801 |
| Speagle, Michael | Lincoln (1); 41 acres, 1800 |
| Speagle, Phillip | Burke (1); 8 acres, 1885 |
| Speagle, R. P. | Burke (1); 14 acres, 1891 |
| Speagle, Solomon | Catawba (1); 6 acres, 1856 |
| Speak, Martin | Rowan (1); 50 acres, 1800 |
| Speake, Richard | Rowan (1); 200 acres, 1789 |
| Speaks, W. M. | Wilkes (1); 5 acres, 1889 |
| Spear Tops Mountain | Mitchell (1); 8 acres, 1881 |
| Spear, Henry | Anson (1), Hawkins TN (1); total 2 grants and 300 acres, 1771-1790 |
| Spear, Jacob | Burke (1); 100 acres, 1813 |
| Spear, John | Edgecombe (2), Beaufort (1); total 3 grants and 1126 acres, 1761 |
| Spear, Lewis | Craven (1); 95 acres, 1850 |
| Spear, Seth | Davidson TN (1); 640 acres, 1789 |
| Spear, William | Beaufort (3), Mecklenburg (1); total 4 grants and 1023 acres, 1784 |
| Speares, Elisha | Cabarrus (1); 45 acres, 1821 |
| Spearhour, Jacob | Surry (2); 500 acres, 1783 |
| Spearhour, Michael | Surry (1); 300 acres, 1783 |
| Spearman, Andrew | New Hanover (3); 195 acres, 1756 |
| Spearman, Edward | New Hanover (11), Bladen (5); total 16 grants and 2604 acres, 1774-1806 |
| Spearman, George | Bladen (1); 200 acres |
| Spearman, Samuel | Onslow (2); 200 acres, 1775 |
| Spearmans Branch | Onslow (2); 65 acres, 1830 |
| Spearpoint, Joseph | Davidson TN (1); 640 acres, 1793 |
| Spearr, Thomas | Montgomery TN (1); 640 acres |
| Spears, Arthur | Halifax (1); 122 acres, 1783 |
| Spears, Benton | Robeson (1); 200 acres, 1794 |
| Spears, Elisha | Cabarrus (1); 22 acres, 1802 |
| Spears, Harris | Robeson (3); 331 acres, 1789 |
| Spears, Isaiah | Cabarrus (4); 166 acres, 1797-1829 |
| Spears, James | Edgecombe (1), Craven (1); total 2 grants and 264 acres, 1823 |
| Spears, John | Duplin (4), Rutherford (1), Cumberland (1); total 6 grants and 1208 acres, 1755-1792 |
| Spears, John A. | Harnett (1); 145 acres, 1901 |
| Spears, Joseph G. | Montgomery (1); 150 acres |
| Spears, Margaret | Tennessee TN (1); 1000 acres, 1796 |
| Spears, Odam | Wilkes (1); 25 acres, 1864 |
| Spears, Robert | Tennessee TN (1); 1000 acres, 1796 |
| Spears, Solomon | Bladen (1); 100 acres, 1779 |
| Spears, Thomas | Montgomery (1), Wilkes (1); total 2 grants and 108 acres, 1783-1881 |
| Spears, William | Mecklenburg (2), Guilford (2), Granville (1), plus 1 grant in 1 other county; total 6 grants and 965 acres, 1761-1799 |
| Speaugh, Christain | Lincoln (1); 150 acres, 1794 |
| Specir, Joseph | Wilkes (1); 50 acres, 1802 |
| Speck, George | Cabarrus (1); 95 acres |
| Specks Branch | Burke (1); 75 acres, 1834 |
| Specks, Aaron Lackey | Iredell (1); 100 acres, 1794 |
| Specks, Aaron Luckey | Iredell (1); 263 acres, 1801 |
| Speculation Line | Polk (1); 91 acres, 1885 |
| Speed, John | Richmond (8); 875 acres, 1787-1800 |
| Speeds Creek | Richmond (4); 1530 acres, 1833-1854 |
| Speeks, Aaron Luckey | Rowan (2); 395 acres, 1787 |
| Speeks, Thomas | Rowan (1), Iredell (1); total 2 grants and 347 acres, 1787 |
| Speer, Aaron | Surry (2); 400 acres, 1779-1784 |
| Speer, Andrew | Surry (7); 2580 acres, 1779-1795 |
| Speer, Benjamin | Surry (1); 50 acres, 1780 |
| Speer, H. | Surry (2); 400 acres |
| Speer, Henry | Surry (139), Stokes (2), Rowan (1), plus 2 grants in 2 other counties; total 144 grants and 30915 acres, 1779-1813 |
| Speer, Jacob | Surry (2); 420 acres, 1779-1802 |
| Speer, Jacob, Jr. | Surry (2); 300 acres, 1780-1802 |
| Speer, James J. | Surry (1); 17 acres, 1829 |
| Speer, John | Surry (5), Buncombe (2), Pitt (1); total 8 grants and 1989 acres, 1783-1813 |
| Speer, Joshua Kennerly | Surry (1); 150 acres, 1787 |
| Speer, Levi | Surry (2); 337 acres, 1780-1806 |
| Speer, Phillip | McDowell (1); 66 acres, 1871 |
| Speer, Richard | Surry (3); 810 acres, 1789-1797 |
| Speer, Robert | Surry (2); 300 acres, 1782-1787 |
| Speer, Samuel | Surry (9); 314 acres, 1799-1835 |
| Speer, William | Pitt (2), Surry (1); total 3 grants and 431 acres, 1782-1905 |
| Speerpoint, Joseph | Davidson TN (1); 640 acres, 1787 |
| Speers, Henry | Surry (1), Rowan (1); total 2 grants and 440 acres, 1783 |
| Speght, Frances | Craven (1); 573 acres |
| Spegle, Martain | Lincoln (1); 100 acres, 1787 |
| Speigel, Moses | Lincoln (1); 25 acres |
| Speigel, Samuel | Lincoln (1); 67 acres |
| Speight, Dempsey | Dobbs (1); 640 acres, 1779 |
| Speight, Francis | Chowan (4), Glasgow (2), Dobbs (2), plus 3 grants in 2 other counties; total 11 grants and 4160 acres, 1743-1797 |
| Speight, James | Sumner TN (1); 365 acres, 1793 |
| Speight, Jeremiah | Gates (1); 252 acres, 1783 |
| Speight, John | Dobbs (1), Craven (1); total 2 grants and 940 acres, 1780-1799 |
| Speight, John W. | Craven (1); 39 acres, 1857 |
| Speight, Joseph | Gates (1), Sumner TN (1); total 2 grants and 811 acres, 1783-1793 |
| Speight, L. C. | Brunswick (1); 25 acres, 1849 |
| Speight, Mary | Craven (1); 185 acres |
| Speight, Moses | Dobbs (1), Sumner TN (1); total 2 grants and 715 acres, 1793 |
| Speight, Richard Dobbs | Eastern District TN (1); 200 acres, 1794 |
| Speight, Samuel | Dobbs (4), Glasgow (2), Greene (1); total 7 grants and 1877 acres, 1779-1803 |
| Speight, Seth | Glasgow (5), Dobbs (4), Greene TN (1); total 10 grants and 1796 acres, 1780-1798 |
| Speight, Simon | Jones (3), Craven (2); total 5 grants and 580 acres, 1764-1784 |
| Speight, Thomas | Craven (4), Perquimans (3), Chowan (1); total 8 grants and 2296 acres, 1696-1787 |
| Speight, William | Craven (12), Dobbs (11), Glasgow (6), plus 6 grants in 5 other counties; total 35 grants and 8505 acres, 1696-1846 |
| Speight, William, Jr. | Craven (2); 525 acres, 1786-1799 |
| Speights Branch | Wake (1); 640 acres, 1779 |
| Speights, Simon | Pitt (1); 0 acres |
| Speights, William | Wake (1); 398 acres, 1779 |
| Speigle, Davault | Lincoln (1); 5 acres, 1814 |
| Speigle, Devault | Lincoln (1); 4 acres, 1812 |
| Speigle, Martin | Lincoln (1); 154 acres, 1789 |
| Speigle, Samuel | Lincoln (2); 137 acres |
| Speir, James | Edgecombe (3); 660 acres, 1742-1758 |
| Speir, John | Edgecombe (2), Pitt (1); total 3 grants and 909 acres, 1739-1802 |
| Speir, William | Pitt (2), Edgecombe (2), Beaufort (1); total 5 grants and 1754 acres, 1740-1802 |
| Spell, H. L. | Sampson (1); 14 acres, 1886 |
| Spell, Hardy | Sampson (2); 30 acres, 1833-1857 |
| Spell, Harris | Johnston (1); 100 acres |
| Spell, J. H. | Sampson (1); 1 acres, 1884 |
| Spell, J. J. | Sampson (3); 44 acres, 1874-1877 |
| Spell, James | Sampson (1); 16 acres, 1845 |
| Spell, James M. | Sampson (1); 495 acres, 1843 |
| Spell, John | Edgecombe (2); 1478 acres, 1754-1782 |
| Spell, Jones | Edgecombe (1); 513 acres, 1761 |
| Spell, L. H. | Sampson (1); 15 acres, 1858 |
| Spell, R. L. | Sampson (2); 152 acres, 1879-1882 |
| Spellar, James | Duplin (1); 30 acres, 1784 |
| Spellars Creek | Martin (1); 400 acres, 1784 |
| Spellars, Thomas | Martin (1); 72 acres |
| Speller, Henry | Bertie (3), Chowan (1); total 4 grants and 1528 acres, 1719-1726 |
| Speller, Thomas | Tyrrell (1), Bertie (1); total 2 grants and 305 acres, 1745-1811 |
| Spelling, Timothy | Bertie (1); 300 acres, 1725 |
| Spellmam, N. J. | Cherokee (1); 100 acres, 1855 |
| Spelman, Harman | Rowan (1); 640 acres, 1784 |
| Spelman, John | Perquimans (1); 350 acres, 1694 |
| Spelman, Simon | Sumner TN (1); 640 acres, 1797 |
| Spence, Alexander | Pasquotank (1); 100 acres, 1715 |
| Spence, Arthur | Currituck (1); 59 acres, 1806 |
| Spence, David | Surry (1), Middle District TN (1), Davidson TN (1); total 3 grants and 3340 acres, 1789-1794 |
| Spence, E. T. | Cumberland (1); 1 acres, 1907 |
| Spence, Elisha | Cumberland (1); 20 acres, 1820 |
| Spence, Graves | Pasquotank (1); 185 acres, 1751 |
| Spence, Hardy | Tyrrell (2); 350 acres, 1832-1847 |
| Spence, Hiziah | Wilkes (1); 50 acres, 1812 |
| Spence, Isaac | Duplin (1); 50 acres, 1799 |
| Spence, James | Pasquotank (1), Davidson TN (1); total 2 grants and 868 acres, 1719-1787 |
| Spence, James H. | Macon (1); 100 acres, 1850 |
| Spence, Job | Sumner TN (1); 274 acres, 1793 |
| Spence, John | Cumberland (8), Wake (1), Surry (1), plus 1 grant in 1 other county; total 11 grants and 1238 acres, 1796-1832 |
| Spence, Joseph | Tyrrell (10); 1857 acres, 1779-1832 |
| Spence, Robert | Tyrrell (3), Randolph (1); total 4 grants and 450 acres, 1794-1821 |
| Spence, Thomas | Surry (3); 650 acres, 1782-1790 |
| Spence, William | Davidson TN (1); 640 acres, 1789 |
| Spencer Creek | Montgomery (4); 550 acres, 1803-1882 |
| Spencer Mountain | Lincoln (1), Gaston (1); total 2 grants and 56 acres, 1902 |
| Spencer's Creek | Montgomery (2); 81 acres, 1851-1908 |
| Spencer, Abraham | Guilford (1); 300 acres, 1784 |
| Spencer, Absolom | Burke (1); 100 acres |
| Spencer, Alexander | Randolph (5), Montgomery (1); total 6 grants and 941 acres, 1840-1852 |
| Spencer, Ama | Montgomery (1); 100 acres, 1844 |
| Spencer, Ambrose | Ashe (2); 45 acres, 1886-1895 |
| Spencer, Ball | Surry (1); 100 acres, 1778 |
| Spencer, Benjamin | Caswell (1); 200 acres, 1783 |
| Spencer, Burrel | Ashe (1); 40 acres, 1805 |
| Spencer, Christopher C. | Hyde (2); 15 acres, 1889 |
| Spencer, Clark | Montgomery (1); 100 acres, 1844 |
| Spencer, Colon G. | Moore (1); 3 acres, 1924 |
| Spencer, Creek | Montgomery (1); 40 acres, 1816 |
| Spencer, David M. | Ashe (1); 50 acres, 1873 |
| Spencer, Edward | Hyde (21); 11600 acres, 1774-1775 |
| Spencer, Elias | Montgomery (2); 200 acres, 1795-1804 |
| Spencer, Elijah | Montgomery (5); 655 acres, 1795-1809 |
| Spencer, Elizabeth | Montgomery (1); 100 acres, 1844 |
| Spencer, Fenner S. | Hyde (1); 7 acres, 1889 |
| Spencer, George | Randolph (1), Montgomery (1); total 2 grants and 160 acres, 1840-1844 |
| Spencer, Greenville | Stokes (1); 50 acres, 1829 |
| Spencer, H. B. | Ashe (1), Hyde (1); total 2 grants and 12 acres, 1883-1891 |
| Spencer, Hardy | Tyrrell (2); 100 acres, 1852 |
| Spencer, Henry | Ashe (1); 45 acres, 1872 |